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ALL / Clinical Sciences
Pneumocytes
Pneumocytes
There are two main types of pneumocytes:| Cell type | Notes |
|---|---|
| Type 1 pneumocytes | Very thin squamous cells which cover around 97% of the alveolar surface |
| Type 2 pneumocytes | Cuboidal cells Secrete surfactant Start to develop around 24 weeks gestation, however adequate surfactant production does not take place until around 35 weeks so premature babies are prone to respiratory distress syndrome Can differentiate into Type 1 pneumocytes during lung damage |
Club cells (previously termed Clara cells) are non-ciliated dome-shaped cells found in the bronchioles. They have a varied role including protecting against the deleterious effects of inhaled toxins and the secretion of glycosaminoglycans and lysozymes.
+PassMedicine Notes
There are two main types of pneumocytes:
Cell type _ Notes| Type 1 pneumocytes_ Very thin squamous cells which cover around 97% of the alveolar surface | Type 2 pneumocytes _ Cuboidal cellsSecrete surfactant
Start to develop around 24 weeks gestation, however adequate surfactant production does not take place until around 35 weeks so premature babies are prone to respiratory distress syndrome
Can differentiate into Type 1 pneumocytes during lung damage|
Club cells (previously termed Clara cells) are non-ciliated dome-shaped cells found in the bronchioles. They have a varied role including protecting against the deleterious effects of inhaled toxins and the secretion of glycosaminoglycans and lysozymes.