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ALL / Cardiology

Ivabradine

Ivabradine

Ivabradine is a class drug which works by reducing the heart rate. It acts on the If ('funny') ion current that is highly expressed in the sinoatrial (SA) node, reducing cardiac pacemaker activity.

Indications
  • angina pectoris
  • chronic heart failure

Ivabradine only works in sinus rhythm
  • in atrial fibrillation the atrial activity is chaotic → SA node is no longer controlling heart rate

Adverse effects
  • visual effects, particular luminous phenomena, are common
  • headache
  • bradycardia, heart block
+PassMedicine Notes

Ivabradine is a class drug which works by reducing the heart rate. It acts on the If ('funny') ion current that is highly expressed in the sinoatrial (SA) node, reducing cardiac pacemaker activity.

Indications
  • angina pectoris
  • chronic heart failure
Ivabradine only works in sinus rhythm
  • in atrial fibrillation the atrial activity is chaotic → SA node is no longer controlling heart rate
Adverse effects
  • visual effects, particular luminous phenomena, are common
  • headache
  • bradycardia, heart block


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