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ALL / Infectious Diseases
Cephalosporins
Cephalosporins
Cephalosporins are a type of β-lactam antibiotic which are bactericidal. They are less susceptible to penicillinases than penicillins.β-lactam antibiotics work by disrupting the synthesis of bacterial cell walls, by inhibiting peptidoglycan cross-linking.
Mechanism of resistance
- Changes to penicillin-binding-proteins (PBPs), which are types of transpeptidases (enzymes produced by bacteria that cross-links peptidoglycan chains to form rigid cell walls)
+PassMedicine Notes
Cephalosporins are a type of #beta#-lactam antibiotic which are bactericidal. They are less susceptible to penicillinases than penicillins.
#beta#-lactam antibiotics work by disrupting the synthesis of bacterial cell walls, by inhibiting peptidoglycan cross-linking.
Mechanism of resistance- Changes to penicillin-binding-proteins (PBPs), which are types of transpeptidases (enzymes produced by bacteria that cross-links peptidoglycan chains to form rigid cell walls)
