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ALL / Neurology

Peripheral neuropathy: demyelinating vs. axonal

Peripheral neuropathy: demyelinating vs. axonal

Demyelinating pathology
  • Guillain-Barre syndrome
  • chronic inflammatory demyelinating polyneuropathy (CIDP)
  • amiodarone
  • hereditary sensorimotor neuropathies (HSMN) type I
  • paraprotein neuropathy

Axonal pathology
  • alcohol
  • diabetes mellitus*
  • vasculitis
  • vitamin B12 deficiency*
  • hereditary sensorimotor neuropathies (HSMN) type II

* may also cause a demyelinating picture
+PassMedicine Notes
Demyelinating pathology
  • Guillain-Barre syndrome
  • chronic inflammatory demyelinating polyneuropathy (CIDP)
  • amiodarone
  • hereditary sensorimotor neuropathies (HSMN) type I
  • paraprotein neuropathy
Axonal pathology
  • alcohol
  • diabetes mellitus*
  • vasculitis
  • vitamin B12 deficiency*
  • hereditary sensorimotor neuropathies (HSMN) type II

* may also cause a demyelinating picture



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