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ALL / Respiratory Medicine

Respiratory physiology: lung volumes

Respiratory physiology: lung volumes

The diagram below demonstrates the lung volumes which may be measured:


Tidal volume (TV)
  • volume inspired or expired with each breath at rest
  • 500ml in males, 350ml in females

Inspiratory reserve volume (IRV) = 2-3 L
  • maximum volume of air that can be inspired at the end of a normal tidal inspiration
  • inspiratory capacity = TV + IRV

Expiratory reserve volume (ERV) = 750ml
  • maximum volume of air that can be expired at the end of a normal tidal expiration
  • significantly reduced in obesity (increased abdominal fat mass pushes up against the diaphragm, reducing the volume of air that can be expelled)

Residual volume (RV) = 1.2L
  • volume of air remaining after maximal expiration
  • increases with age
  • RV = FRC - ERV

Functional residual capacity (FRC)
  • the volume in the lungs at the end-expiratory position
  • FRC = ERV + RV

Vital capacity (VC) = 5L
  • maximum volume of air that can be expired after a maximal inspiration
  • 4,500ml in males, 3,500 mls in females
  • decreases with age
  • VC = inspiratory capacity + ERV

Total lung capacity (TLC) is the sum of the vital capacity + residual volume

Physiological dead space (VD)
  • VD = tidal volume * (PaCO2 - PeCO2) / PaCO2
  • where PeCO2 = expired air CO2
+PassMedicine Notes

The diagram below demonstrates the lung volumes which may be measured:

swb023.jpg

Tidal volume (TV)
  • volume inspired or expired with each breath at rest
  • 500ml in males, 350ml in females
Inspiratory reserve volume (IRV) = 2-3 L
  • maximum volume of air that can be inspired at the end of a normal tidal inspiration
  • inspiratory capacity = TV + IRV
Expiratory reserve volume (ERV) = 750ml
  • maximum volume of air that can be expired at the end of a normal tidal expiration
  • significantly reduced in obesity (increased abdominal fat mass pushes up against the diaphragm, reducing the volume of air that can be expelled)
Residual volume (RV) = 1.2L
  • volume of air remaining after maximal expiration
  • increases with age
  • RV = FRC - ERV
Functional residual capacity (FRC)
  • the volume in the lungs at the end-expiratory position
  • FRC = ERV + RV
Vital capacity (VC) = 5L
  • maximum volume of air that can be expired after a maximal inspiration
  • 4,500ml in males, 3,500 mls in females
  • decreases with age
  • VC = inspiratory capacity + ERV

Total lung capacity (TLC) is the sum of the vital capacity + residual volume

Physiological dead space (VD)
  • VD = tidal volume * (PaCO2 - PeCO2) / PaCO2
  • where PeCO2 = expired air CO2


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