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ALL / Respiratory Medicine

Pulmonary eosinophilia

Pulmonary eosinophilia

Pulmonary eosinophilia describes a situation where there are increased numbers of eosinophils in the lung airways and parenchyma. This is generally associated with a blood eosinophilia.

Causes of pulmonary eosinophilia
  • Churg-Strauss syndrome
  • allergic bronchopulmonary aspergillosis (ABPA)
  • Loffler's syndrome
  • eosinophilic pneumonia
  • hypereosinophilic syndrome
  • tropical pulmonary eosinophilia
  • drugs: nitrofurantoin, sulphonamides
  • less common: Wegener's granulomatosis

Loffler's syndrome
  • transient CXR shadowing and blood eosinophilia
  • thought to be due to parasites such as Ascaris lumbricoides causing an alveolar reaction
  • presents with a fever, cough and night sweats which often last for less than 2 weeks.
  • generally a self-limiting disease

Acute eosinophilic pneumonia
  • highly responsive to steroids

Tropical pulmonary eosinophilia
  • associated with Wuchereria bancrofti infection
+PassMedicine Notes

Pulmonary eosinophilia describes a situation where there are increased numbers of eosinophils in the lung airways and parenchyma. This is generally associated with a blood eosinophilia.

Causes of pulmonary eosinophilia
  • Churg-Strauss syndrome
  • allergic bronchopulmonary aspergillosis (ABPA)
  • Loffler's syndrome
  • eosinophilic pneumonia
  • hypereosinophilic syndrome
  • tropical pulmonary eosinophilia
  • drugs: nitrofurantoin, sulphonamides
  • less common: Wegener's granulomatosis
Loffler's syndrome
  • transient CXR shadowing and blood eosinophilia
  • thought to be due to parasites such as Ascaris lumbricoides causing an alveolar reaction
  • presents with a fever, cough and night sweats which often last for less than 2 weeks.
  • generally a self-limiting disease
Acute eosinophilic pneumonia
  • highly responsive to steroids
Tropical pulmonary eosinophilia
  • associated with Wuchereria bancrofti infection


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