Brain lesions
The following neurological disorders/features may allow localisation of a brain lesion:
Gross anatomy
Parietal lobe lesions
- sensory inattention
sensory inattention
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- apraxias
Parietal lobe lesions may cause apraxias
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Importance: 31
- astereognosis
Parietal lobe lesions may cause astereognosis
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Importance: 59
(tactile agnosia) - inferior homonymous quadrantanopia
Parietal lobe lesions may cause inferior homonymous quadrantanopia
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Importance: 30
- Gerstmann's syndrome
Parietal lobe lesions may cause Gerstmann's syndrome
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Importance: 52
(lesion of dominant parietal): alexiaParietal lobe lesions may cause alexia
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Importance: 25
, acalculiaParietal lobe lesions may cause acalculia
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Importance: 73
, finger agnosia and right-left disorientation
Occipital lobe lesions
- homonymous hemianopia (with macula sparing)
Occipital lobe lesions may cause homonymous hemianopia (with macula sparing)
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Importance: 2
- cortical blindness
Occipital lobe lesions may cause cortical blindness
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Importance: 41
- visual agnosia
Occipital lobe lesions may cause visual agnosia
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Importance: 17
Temporal lobe lesion
- Wernicke's aphasia
Temporal lobe lesions may cause Wernicke's aphasia
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Importance: 27
: this area 'forms' the speech before 'sending it' to Brocas area. Lesions result in word substituion, neologisms but speech remains fluentLesions result in word substituion, neologisms but speech remains fluent
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- superior homonymous quadrantanopia
Temporal lobe lesions may cause superior homonymous quadrantanopia
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Importance: 32
- auditory agnosia
Temporal lobe lesions may cause auditory agnosia
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Importance: 68
- prosopagnosia (difficulty recognising faces)
prosopagnosia (difficulty recognising faces)
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Frontal lobes lesions
- expressive (Broca's) aphasia
Frontal lobe lesions may cause expressive (Broca's) aphasia
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Importance: 26
: located on the posterior aspect of the frontal lobe, in the inferior frontal gyrus. Speech is non-fluent, laboured, and halting - disinhibition
Frontal lobe lesions may cause disinhibition
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Importance: 7
- perseveration
Frontal lobe lesions may cause perseveration
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Importance: 75
- anosmia
anosmia
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- inability to generate a list
Frontal lobe lesions may cause inability to generate a list
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Importance: 53
Cerebellum lesions
- midline lesions: gait and truncal ataxia
- hemisphere lesions: intention tremor, past pointing, dysdiadokinesis, nystagmus
More specific areas
| Area | Associated conditions |
|---|
| Medial thalamus and mammillary bodies of the hypothalamus Medial thalamus and mammillary bodies of the hypothalamus lesions may cause Wernicke and Korsakoff syndrome You've never been tested on this concept You've not yet rated this concept. Importance: 36 | Wernicke and Korsakoff syndrome |
| Subthalamic nucleus of the basal ganglia Subthalamic nucleus of the basal ganglia lesions may cause hemiballism You've never been tested on this concept You've not yet rated this concept. Importance: 69 | Hemiballism |
| Striatum (caudate nucleus) of the basal ganglia Striatum (caudate nucleus) of the basal ganglia lesions may cause Huntington chorea You've never been tested on this concept You've not yet rated this concept. Importance: 25 | Huntington chorea |
| Substantia nigra of the basal ganglia Substantia nigra of the basal ganglia lesions may cause Parkinson's disease You've never been tested on this concept You've not yet rated this concept. Importance: 31 | Parkinson's disease |
| Amygdala Amygdala lesions may cause Kluver-Bucy syndrome You've never been tested on this concept You've not yet rated this concept. Importance: 12 | Kluver-Bucy syndrome (hypersexuality, hyperorality, hyperphagia, visual agnosia |
+PassMedicine Notes
The following neurological disorders/features may allow localisation of a brain lesion:
Gross anatomy
Parietal lobe lesions
- sensory inattention
- apraxias
- astereognosis (tactile agnosia)
- inferior homonymous quadrantanopia
- Gerstmann's syndrome (lesion of dominant parietal): alexia, acalculia, finger agnosia and right-left disorientation
Occipital lobe lesions
- homonymous hemianopia (with macula sparing)
- cortical blindness
- visual agnosia
Temporal lobe lesion
- Wernicke's aphasia: this area 'forms' the speech before 'sending it' to Brocas area. Lesions result in word substituion, neologisms but speech remains fluent
- superior homonymous quadrantanopia
- auditory agnosia
- prosopagnosia (difficulty recognising faces)
Frontal lobes lesions
- expressive (Broca's) aphasia: located on the posterior aspect of the frontal lobe, in the inferior frontal gyrus. Speech is non-fluent, laboured, and halting
- disinhibition
- perseveration
- anosmia
- inability to generate a list
Cerebellum lesions
- midline lesions: gait and truncal ataxia
- hemisphere lesions: intention tremor, past pointing, dysdiadokinesis, nystagmus
More specific areas
Area _ Associated conditions|
Medial thalamus and mammillary bodies of the hypothalamus_ Wernicke and Korsakoff syndrome|
Subthalamic nucleus of the basal ganglia _ Hemiballism|
Striatum (caudate nucleus) of the basal ganglia _ Huntington chorea|
Substantia nigra of the basal ganglia _ Parkinson's disease|
Amygdala _ Kluver-Bucy syndrome (hypersexuality, hyperorality, hyperphagia, visual agnosia|