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ALL / Respiratory Medicine

Lung cancer: carcinoid

Lung cancer: carcinoid

The vast majority of bronchial adenomas are carcinoid tumours, arising from the amine precursor uptake and decarboxylation (APUD) system, like small cell tumours. Lung carcinoid accounts 1% of lung tumours and for 10% of carcinoid tumours. The term bronchial adenoma is being phased out.

Lung carcinoid
  • typical age = 40-50 years
  • smoking not risk factor
  • slow growing: e.g. long history of cough, recurrent haemoptysis
  • often centrally located and not seen on CXR
  • 'cherry red ball' often seen on bronchoscopy
  • carcinoid syndrome itself is rare (associated with liver metastases)

Management
  • surgical resection
  • if no metastases then 90% survival at 5 years

Pathophysiology of carcinoid tumours
+PassMedicine Notes

The vast majority of bronchial adenomas are carcinoid tumours, arising from the amine precursor uptake and decarboxylation (APUD) system, like small cell tumours. Lung carcinoid accounts 1% of lung tumours and for 10% of carcinoid tumours. The term bronchial adenoma is being phased out.

Lung carcinoid
  • typical age = 40-50 years
  • smoking not risk factor
  • slow growing: e.g. long history of cough, recurrent haemoptysis
  • often centrally located and not seen on CXR
  • 'cherry red ball' often seen on bronchoscopy
  • carcinoid syndrome itself is rare (associated with liver metastases)
Management
  • surgical resection
  • if no metastases then 90% survival at 5 years


Media
Carcinoid syndrome
Osmosis - YouTube
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Carcinoid syndrome
YouTube
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