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ALL / Ophthalmology

Central retinal vein occlusion

Central retinal vein occlusion

Central retinal vein occlusion (CRVO) is a differential for sudden painless loss of vision.

Risk factors
  • increasing age
  • hypertension
  • cardiovascular disease
  • glaucoma
  • polycythaemia

Features
  • sudden, painless reduction or loss of visual acuity, usually unilaterally
  • fundoscopy
    • widespread hyperaemia
    • severe retinal haemorrhages - 'stormy sunset'

A key differential is branch retinal vein occlusion (BRVO) - this occurs when a vein in the distal retinal venous system is occluded and is thought to occur due to blockage of retinal veins at arteriovenous crossings. It results in a more limited area of the fundus being affected.

Fundoscopy showing branch retinal vein occlusion
BRVO vs CRVO - typical fundoscopy findings

Management
  • the majority of patients are managed conservatively
  • indications for treatment in patients with CRVO include:
    • macular oedema - intravitreal anti-vascular endothelial growth factor (VEGF) agents
    • retinal neovascularization - laser photocoagulation

Fundoscopy image showing a central retinal vein occlusion
+PassMedicine Notes

Central retinal vein occlusion (CRVO) is a differential for sudden painless loss of vision.

Risk factors
  • increasing age
  • hypertension
  • cardiovascular disease
  • glaucoma
  • polycythaemia
Features
  • sudden, painless reduction or loss of visual acuity, usually unilaterally
  • fundoscopy
    • widespread hyperaemia
    • severe retinal haemorrhages - 'stormy sunset'

A key differential is branch retinal vein occlusion (BRVO) - this occurs when a vein in the distal retinal venous system is occluded and is thought to occur due to blockage of retinal veins at arteriovenous crossings. It results in a more limited area of the fundus being affected.

Management
  • the majority of patients are managed conservatively
  • indications for treatment in patients with CRVO include:
    • macular oedema - intravitreal anti-vascular endothelial growth factor (VEGF) agents
    • retinal neovascularization - laser photocoagulation


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