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ALL / Cardiology

Nicorandil

Nicorandil

Nicorandil is a vasodilatory drug used to treat angina. It is a potassium-channel activator with vasodilation is through activation of guanylyl cyclase which results in increase cGMP.

Adverse effects
  • headache
  • flushing
  • skin, mucosal and eye ulceration
    • gastrointestinal ulcers including anal ulceration

Contraindications
  • left ventricular failure
+PassMedicine Notes

Nicorandil is a vasodilatory drug used to treat angina. It is a potassium-channel activator with vasodilation is through activation of guanylyl cyclase which results in increase cGMP.

Adverse effects
  • headache
  • flushing
  • skin, mucosal and eye ulceration
    • gastrointestinal ulcers including anal ulceration
Contraindications
  • left ventricular failure


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