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Ankylosing spondylitis: features

Ankylosing spondylitis: features

Ankylosing spondylitis is a HLA-B27 associated spondyloarthropathy. It typically presents in males (sex ratio 3:1) aged 20-30 years old.

Features
  • typically a young man who presents with lower back pain and stiffness of insidious onset
  • stiffness is usually worse in the morning and improves with exercise
  • the patient may experience pain at night which improves on getting up

Clinical examination
  • reduced lateral flexion
  • reduced forward flexion - Schober's test - a line is drawn 10 cm above and 5 cm below the back dimples (dimples of Venus). The distance between the two lines should increase by more than 5 cm when the patient bends as far forward as possible
  • reduced chest expansion

Other features - the 'A's
  • Apical fibrosis
  • Anterior uveitis
  • Aortic regurgitation
  • Achilles tendonitis
  • AV node block
  • Amyloidosis
  • and cauda equina syndrome
  • peripheral arthritis (25%, more common if female)
+PassMedicine Notes

Ankylosing spondylitis is a HLA-B27 associated spondyloarthropathy. It typically presents in males (sex ratio 3:1) aged 20-30 years old.

Features
  • typically a young man who presents with lower back pain and stiffness of insidious onset
  • stiffness is usually worse in the morning and improves with exercise
  • the patient may experience pain at night which improves on getting up
Clinical examination
  • reduced lateral flexion
  • reduced forward flexion - Schober's test - a line is drawn 10 cm above and 5 cm below the back dimples (dimples of Venus). The distance between the two lines should increase by more than 5 cm when the patient bends as far forward as possible
  • reduced chest expansion
Other features - the 'A's
  • Apical fibrosis
  • Anterior uveitis
  • Aortic regurgitation
  • Achilles tendonitis
  • AV node block
  • Amyloidosis
  • and cauda equina syndrome
  • peripheral arthritis (25%, more common if female)


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