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ALL / Dermatology
Pellagra
Pellagra
Pellagra is a caused by nicotinic acid (niacin) deficiency. The classical features are the 3 D's - dermatitis, diarrhoea and dementia.Pellagra may occur as a consequence of isoniazid therapy (isoniazid inhibits the conversion of tryptophan to niacin) and it is more common in alcoholics.
Features
- dermatitis (brown scaly rash on sun-exposed sites - termed Casal's necklace if around neck)
- diarrhoea
- dementia, depression
- death if not treated
+PassMedicine Notes
Pellagra is a caused by nicotinic acid (niacin) deficiency. The classical features are the 3 D's - dermatitis, diarrhoea and dementia.
Pellagra may occur as a consequence of isoniazid therapy (isoniazid inhibits the conversion of tryptophan to niacin) and it is more common in alcoholics.
Features- dermatitis (brown scaly rash on sun-exposed sites - termed Casal's necklace if around neck)
- diarrhoea
- dementia, depression
- death if not treated