Thin basement membrane disease

Thin basement membrane disease

An inherited disorder of type IV collagen that causes thinning of the basement membrane. It may affect up to 5% of the population and about 30% patients report a family history of haematuria. Diagnosis is usually based on the history of persistent haematuria, normal kidney function and family history of haematuria without kidney failure. It is generally a benign disorder and biopsy is rarely indicated.

+PassMedicine Notes

An inherited disorder of type IV collagen that causes thinning of the basement membrane. It may affect up to 5% of the population and about 30% patients report a family history of haematuria. Diagnosis is usually based on the history of persistent haematuria, normal kidney function and family history of haematuria without kidney failure. It is generally a benign disorder and biopsy is rarely indicated.