Highlighter is on. Drag to highlight text. Click a highlight to remove it.
ALL / Respiratory Medicine

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

Eosinophilic granulomatosis with polyangiitis (EGPA) is now the preferred term for Churg-Strauss syndrome. It is an ANCA associated small-medium vessel vasculitis.

Features
  • asthma
  • blood eosinophilia (e.g. > 10%)
  • paranasal sinusitis
  • mononeuritis multiplex
  • renal involvement occurs in around 20%
  • pANCA positive in 60%

Comparison of granulomatosis with polyangiitis and Churg-Strauss syndrome

Leukotriene receptor antagonists may precipitate the disease.
+PassMedicine Notes

Eosinophilic granulomatosis with polyangiitis (EGPA) is now the preferred term for Churg-Strauss syndrome. It is an ANCA associated small-medium vessel vasculitis.

Features
  • asthma
  • blood eosinophilia (e.g. > 10%)
  • paranasal sinusitis
  • mononeuritis multiplex
  • renal involvement occurs in around 20%
  • pANCA positive in 60%
pdd902.png Comparison of granulomatosis with polyangiitis and Churg-Strauss syndrome

Leukotriene receptor antagonists may precipitate the disease.



Saved ✓

MEDIA