Vitamin D

Vitamin D

Vitamin D is a fat-soluble vitamin that plays a key role in calcium and phosphate metabolism. It is converted into the prohormone calcifediol in the liver. Circulating calcifediol is then converted into calcitriol (the biologically active form of vitamin D) in the kidneys

kidneys

You've never been tested on this concept

You've not yet rated this concept.

.

Sources

• vitamin D2 (ergocalciferol): plants
• vitamin D3 (cholecalciferol): dairy products, can be synthesised by the skin from sunlight

Functions

• increases plasma calcium and plasma phosphate
  increases plasma calcium and plasma phosphate
  You've never been tested on this concept
  You've not yet rated this concept.
• increases renal tubular reabsorption and gut absorption of calcium
  Vitamin D increases serum calcium primarily through raising its absorption via the small intestine
  You've never been tested on this concept
  You've not yet rated this concept.
  Importance: 80
• increases osteoclastic activity
• increases renal phosphate reabsorption

Consequences of vitamin D deficiency:

• rickets
  rickets
  You've never been tested on this concept
  You've not yet rated this concept.
  : seen in children
• osteomalacia: seen in adults

+PassMedicine Notes

Vitamin D is a fat-soluble vitamin that plays a key role in calcium and phosphate metabolism. It is converted into the prohormone calcifediol in the liver. Circulating calcifediol is then converted into calcitriol (the biologically active form of vitamin D) in the kidneys.

Sources

• vitamin D2 (ergocalciferol): plants
• vitamin D3 (cholecalciferol): dairy products, can be synthesised by the skin from sunlight

Functions

• increases plasma calcium and plasma phosphate
• increases renal tubular reabsorption and gut absorption of calcium
• increases osteoclastic activity
• increases renal phosphate reabsorption

Consequences of vitamin D deficiency:

• rickets: seen in children
• osteomalacia: seen in adults