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ALL / Pharmacology

Octreotide

Octreotide

Overview
  • long-acting analogue of somatostatin
  • somatostatin is released from D cells of pancreas and inhibits the release of growth hormone, glucagon and insulin

Uses
  • acute treatment of variceal haemorrhage
  • acromegaly
  • carcinoid syndrome
  • prevent complications following pancreatic surgery
  • VIPomas
  • refractory diarrhoea

Adverse effects
  • gallstones (secondary to biliary stasis)
+PassMedicine Notes
Overview
  • long-acting analogue of somatostatin
  • somatostatin is released from D cells of pancreas and inhibits the release of growth hormone, glucagon and insulin
Uses
  • acute treatment of variceal haemorrhage
  • acromegaly
  • carcinoid syndrome
  • prevent complications following pancreatic surgery
  • VIPomas
  • refractory diarrhoea
Adverse effects
  • gallstones (secondary to biliary stasis)


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