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ALL / Dermatology

Erythema nodosum

Erythema nodosum

Overview
  • inflammation of subcutaneous fat
  • typically causes tender, erythematous, nodular lesions
  • usually occurs over shins, may also occur elsewhere (e.g. forearms, thighs)
  • usually resolves within 6 weeks
  • lesions heal without scarring

Causes
  • infection
    • streptococci
    • tuberculosis
    • brucellosis
  • systemic disease
    • sarcoidosis
    • inflammatory bowel disease
    • Behcet's
  • malignancy/lymphoma
  • drugs
    • penicillins
    • sulphonamides
    • combined oral contraceptive pill
  • pregnancy

Investigation for underlying causes
  • chest x-ray (to assess for sarcoidosis, tuberculosis, other pulmonary infections, and lymphoma)
  • Throat swab for Group A strep
  • FBC, CRP

Erythema nodosum
Erythema nodosum
Erythema nodosum
This patient developed erythema nodosum secondary to streptococcal infection
Close-up of an erythema nodosum lesion
Example of erythema nodoum in an individual with darker skin
+PassMedicine Notes
Overview
  • inflammation of subcutaneous fat
  • typically causes tender, erythematous, nodular lesions
  • usually occurs over shins, may also occur elsewhere (e.g. forearms, thighs)
  • usually resolves within 6 weeks
  • lesions heal without scarring
Causes
  • infection
    • streptococci
    • tuberculosis
    • brucellosis
  • systemic disease
    • sarcoidosis
    • inflammatory bowel disease
    • Behcet's
  • malignancy/lymphoma
  • drugs
    • penicillins
    • sulphonamides
    • combined oral contraceptive pill
  • pregnancy
Investigation for underlying causes
  • chest x-ray (to assess for sarcoidosis, tuberculosis, other pulmonary infections, and lymphoma)
  • Throat swab for Group A strep
  • FBC, CRP


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