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Nephrotic syndrome: causes

Nephrotic syndrome: causes

Primary glomerulonephritis accounts for around 80% of cases
  • minimal change glomerulonephritis (causes 80% in children, 30% in adults)
  • membranous glomerulonephritis
  • focal segmental glomerulosclerosis
  • membranoproliferative glomerulonephritis

Systemic disease (about 20%)
  • diabetes mellitus
  • systemic lupus erythematosus
  • amyloidosis

Drugs
  • gold (sodium aurothiomalate), penicillamine

Others
  • congenital
  • neoplasia: carcinoma, lymphoma, leukaemia, myeloma
  • infection: bacterial endocarditis, hepatitis B, malaria

Diagram showing the glomerulonephritides and how they typically present
+PassMedicine Notes
Primary glomerulonephritis accounts for around 80% of cases
  • minimal change glomerulonephritis (causes 80% in children, 30% in adults)
  • membranous glomerulonephritis
  • focal segmental glomerulosclerosis
  • membranoproliferative glomerulonephritis
Systemic disease (about 20%)
  • diabetes mellitus
  • systemic lupus erythematosus
  • amyloidosis
Drugs
  • gold (sodium aurothiomalate), penicillamine
Others
  • congenital
  • neoplasia: carcinoma, lymphoma, leukaemia, myeloma
  • infection: bacterial endocarditis, hepatitis B, malaria
pdd907.png Diagram showing the glomerulonephritides and how they typically present

Media
Nephrotic Syndrome - Types and pathology (histology)
Armando Hasudungan - YouTube
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Nephrotic Syndrome - Types and pathology (histology)
Rhesus Medicine - YouTube
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Nephrotic Syndrome Explained Clearly
Armando Hasudungan - YouTube
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Nephrotic Syndrome Explained Clearly
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Nephrotic Syndrome - Overview
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Nephrotic Syndrome - Overview
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