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Remnant hyperlipidaemia

Remnant hyperlipidaemia

Overview
  • rare cause of mixed hyperlipidaemia (raised cholesterol and triglyceride levels)
  • also known as Fredrickson type III hyperlipidaemia, broad-beta disease and dysbetalipoproteinaemia
  • associated with apo-e2 homozygosity
  • high incidence of ischaemic heart disease and peripheral vascular disease
  • thought to be caused by impaired removal of intermediate density lipoprotein from the circulation by the liver

Features
  • yellow palmar creases
  • palmer xanthomas
  • tuberous xanthomas

Management
  • fibrates are first line treatment
+PassMedicine Notes
Overview
  • rare cause of mixed hyperlipidaemia (raised cholesterol and triglyceride levels)
  • also known as Fredrickson type III hyperlipidaemia, broad-beta disease and dysbetalipoproteinaemia
  • associated with apo-e2 homozygosity
  • high incidence of ischaemic heart disease and peripheral vascular disease
  • thought to be caused by impaired removal of intermediate density lipoprotein from the circulation by the liver
Features
  • yellow palmar creases
  • palmer xanthomas
  • tuberous xanthomas
Management
  • fibrates are first line treatment


Media
Familial Dyslipidemias
Dirty USMLE - YouTube
👍 19 👎 1
Familial Dyslipidemias
YouTube
👍 19 👎 1
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