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ALL / Cardiology

Aortic stenosis

Aortic stenosis

Clinical features of symptomatic disease
  • chest pain
  • dyspnoea
  • syncope / presyncope (e.g. exertional dizziness)
  • murmur
    • an ejection systolic murmur (ESM) is classically seen in aortic stenosis
    • classically radiates to the carotids
    • this is decreased following the Valsalva manoeuvre

Features of severe aortic stenosis
  • narrow pulse pressure
  • slow rising pulse
  • delayed ESM
  • soft/absent S2
  • S4
  • thrill
  • duration of murmur
  • left ventricular hypertrophy or failure

Causes of aortic stenosis
  • degenerative calcification (most common cause in older patients > 65 years)
  • bicuspid aortic valve (most common cause in younger patients < 65 years)
  • William's syndrome (supravalvular aortic stenosis)
  • post-rheumatic disease
  • subvalvular: HOCM

Management
  • if asymptomatic then observe the patient is a general rule
  • if symptomatic then valve replacement
  • if asymptomatic but valvular gradient > 40 mmHg and with features such as left ventricular systolic dysfunction then consider surgery
  • options for aortic valve replacement (AVR) include:
    • surgical AVR is the treatment of choice for young, low/medium operative risk patients. Cardiovascular disease may coexist. For this reason, an angiogram is often done prior to surgery so that the procedures can be combined
    • transcatheter AVR (TAVR) is used for patients with a high operative risk
  • balloon valvuloplasty
    • may be used in children with no aortic valve calcification
    • in adults limited to patients with critical aortic stenosis who are not fit for valve replacement

+PassMedicine Notes
Clinical features of symptomatic disease
  • chest pain
  • dyspnoea
  • syncope / presyncope (e.g. exertional dizziness)
  • murmur
    • an ejection systolic murmur (ESM) is classically seen in aortic stenosis
    • classically radiates to the carotids
    • this is decreased following the Valsalva manoeuvre
Features of severe aortic stenosis
  • narrow pulse pressure
  • slow rising pulse
  • delayed ESM
  • soft/absent S2
  • S4
  • thrill
  • duration of murmur
  • left ventricular hypertrophy or failure
Causes of aortic stenosis
  • degenerative calcification (most common cause in older patients > 65 years)
  • bicuspid aortic valve (most common cause in younger patients < 65 years)
  • William's syndrome (supravalvular aortic stenosis)
  • post-rheumatic disease
  • subvalvular: HOCM
Management
  • if asymptomatic then observe the patient is a general rule
  • if symptomatic then valve replacement
  • if asymptomatic but valvular gradient > 40 mmHg and with features such as left ventricular systolic dysfunction then consider surgery
  • options for aortic valve replacement (AVR) include:
    • surgical AVR is the treatment of choice for young, low/medium operative risk patients. Cardiovascular disease may coexist. For this reason, an angiogram is often done prior to surgery so that the procedures can be combined
    • transcatheter AVR (TAVR) is used for patients with a high operative risk
  • balloon valvuloplasty
    • may be used in children with no aortic valve calcification
    • in adults limited to patients with critical aortic stenosis who are not fit for valve replacement

Aortic Stenosis Management Pathway



Media
Aortic stenosis
Armando Hasudungan - YouTube
👍 21 👎 1
Aortic stenosis
Thinklabs - YouTube
👍 21 👎 1
Aortic stenosis murmur - REQUIRES HEADPHONES
Osmosis - YouTube
👍 28 👎 2
Links
European Society of Cardiology
👍 24👎 16
2021 Valvular heart disease guidelines
American Heart Association
👍 22👎 16
Guidelines on the management of valvular heart disease
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