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Aortic dissection: features and classification

Aortic dissection: features and classification

Aortic dissection is a rare but serious cause of chest pain.

Pathophysiology
  • tear in the tunica intima of the wall of the aorta

Associations
  • hypertension: the most important risk factor
  • trauma
  • bicuspid aortic valve
  • collagens: Marfan's syndrome, Ehlers-Danlos syndrome
  • Turner's and Noonan's syndrome
  • pregnancy
  • syphilis

Features:
  • chest/back pain
    • typically severe and 'sharp', 'tearing' in nature
    • pain is typically maximal at onset
    • classically chest pain is more common in type A dissection and upper back pain is more common in type B dissection. However, there is considerable overlap and both chest and back pain are present in many patients
  • pulse deficit
    • weak or absent carotid, brachial, or femoral pulse
    • variation (>20 mmHg) in systolic blood pressure between the arms
  • aortic regurgitation
  • hypertension
  • other features may result from the involvement of specific arteries. For example:
    • coronary arteries → angina
    • spinal arteries → paraplegia
    • distal aorta → limb ischaemia
  • the majority of patients have no or non-specific ECG changes. In a minority of patients, ST-segment elevation may be seen in the inferior leads

Classification

Stanford classification
  • type A - ascending aorta, 2/3 of cases
  • type B - descending aorta, distal to left subclavian origin, 1/3 of cases

DeBakey classification
  • type I - originates in ascending aorta, propagates to at least the aortic arch and possibly beyond it distally
  • type II - originates in and is confined to the ascending aorta
  • type III - originates in descending aorta, rarely extends proximally but will extend distally

Stanford type A / DeBakey type I
Stanford type A / DeBakey type II
Stanford type B / DeBakey type III
+PassMedicine Notes

Aortic dissection is a rare but serious cause of chest pain.

Pathophysiology
  • tear in the tunica intima of the wall of the aorta
Associations
  • hypertension: the most important risk factor
  • trauma
  • bicuspid aortic valve
  • collagens: Marfan's syndrome, Ehlers-Danlos syndrome
  • Turner's and Noonan's syndrome
  • pregnancy
  • syphilis
Features:
  • chest/back pain
    • typically severe and 'sharp', 'tearing' in nature
    • pain is typically maximal at onset
    • classically chest pain is more common in type A dissection and upper back pain is more common in type B dissection. However, there is considerable overlap and both chest and back pain are present in many patients
  • pulse deficit
    • weak or absent carotid, brachial, or femoral pulse
    • variation (>20 mmHg) in systolic blood pressure between the arms
  • aortic regurgitation
  • hypertension
  • other features may result from the involvement of specific arteries. For example:
    • coronary arteries --> angina
    • spinal arteries --> paraplegia
    • distal aorta --> limb ischaemia
  • the majority of patients have no or non-specific ECG changes. In a minority of patients, ST-segment elevation may be seen in the inferior leads

Classification

Stanford classification
  • type A - ascending aorta, 2/3 of cases
  • type B - descending aorta, distal to left subclavian origin, 1/3 of cases
DeBakey classification
  • type I - originates in ascending aorta, propagates to at least the aortic arch and possibly beyond it distally
  • type II - originates in and is confined to the ascending aorta
  • type III - originates in descending aorta, rarely extends proximally but will extend distally


Media
Understanding Aortic Dissection
Zero To Finals - YouTube
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Understanding Aortic Dissection
Osmosis - YouTube
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Aortic dissection
YouTube
👍 20 👎 8
Aortic dissection
YouTube
👍 20 👎 8
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